Philippe Huot Selected Research

(R)- (N- (3- (4'- fluorophenyl)- 3- (4'- phenylphenoxy)propyl))sarcosine

8/2022	Effect of glycine transporter 1 inhibition with bitopertin on parkinsonism and L-DOPA induced dyskinesia in the 6-OHDA-lesioned rat.
11/2021	Effect of the glycine transporter 1 inhibitor ALX-5407 on dyskinesia, psychosis-like behaviours and parkinsonism in the MPTP-lesioned marmoset.

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Philippe Huot Research Topics

Disease

67	Parkinson Disease (Parkinson's Disease) 04/2024 - 01/2007
64	Dyskinesias (Dyskinesia) 04/2024 - 01/2010
31	Psychotic Disorders (Schizoaffective Disorder) 10/2023 - 02/2011
28	Parkinsonian Disorders (Parkinsonism) 10/2023 - 01/2010
3	Schizophrenia (Dementia Praecox) 10/2023 - 09/2018
3	Tremor (Tremors) 01/2017 - 10/2013
2	Dementia (Dementias) 07/2023 - 01/2022
2	Epilepsy (Aura) 07/2020 - 10/2019
2	Hallucinations (Hallucination) 05/2020 - 05/2012
1	Nervous System Diseases (Neurological Disorders) 01/2024
1	Restless Legs Syndrome (Restless Legs) 01/2024
1	Bacteremia 01/2024
1	Brain Diseases (Brain Disorder) 01/2024
1	Delirium 01/2024
1	Fibrosis (Cirrhosis) 01/2024
1	Discitis 01/2024
1	Drug-Induced Dyskinesia (Dyskinesia, Drug Induced) 07/2023
1	Bullous Pemphigoid (Pemphigoid) 01/2023
1	Cognitive Dysfunction 01/2022
1	Mental Disorders (Mental Disorder) 09/2018
1	Movement Disorders (Movement Disorder) 01/2017
1	Tardive Dyskinesia 01/2017
1	Psychomotor Agitation (Akathisia) 01/2017
1	Diabetes Mellitus 03/2015

Drug/Important Bio-Agent (IBA)

67	Levodopa (L Dopa)FDA LinkGeneric 04/2024 - 01/2007
36	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA 10/2023 - 01/2010
20	Serotonin (5 Hydroxytryptamine)IBA 07/2023 - 10/2013
14	Dopamine (Intropin)FDA LinkGeneric 10/2023 - 01/2008
10	Oxidopamine (6 Hydroxydopamine)IBA 04/2024 - 01/2019
9	Glutamic Acid (Glutamate)FDA Link 04/2024 - 09/2018
6	Ondansetron (Zofran)FDA LinkGeneric 04/2022 - 10/2019
6	5-HT2A Serotonin Receptor (5 HT2A Receptor)IBA 02/2019 - 10/2011
4	metabotropic glutamate receptor 2IBA 10/2023 - 09/2018
4	5-HT1A Serotonin ReceptorIBA 10/2015 - 10/2011
3	salicylhydroxamic acid (SHAM)IBA 04/2024 - 04/2022
3	Clozapine (Clozaril)FDA LinkGeneric 04/2024 - 05/2012
3	Glycine Plasma Membrane Transport ProteinsIBA 01/2023 - 11/2021
3	Amantadine (Aman)FDA LinkGeneric 01/2023 - 10/2013
3	Granisetron (Kytril)FDA LinkGeneric 04/2022 - 01/2021
3	Monoamine Oxidase (MAO)IBA 12/2020 - 11/2020
3	Dopamine Plasma Membrane Transport Proteins (Dopamine Transporter)IBA 01/2016 - 01/2015
2	Glycine (Aminoacetic Acid)FDA LinkGeneric 04/2024 - 11/2021
2	Dopamine Agonists (Dopamine Agonist)IBA 01/2024 - 01/2023
2	Metabotropic Glutamate Receptors (Metabotropic Glutamate Receptor)IBA 08/2023 - 01/2023
2	(4- (3- fluoro- 5- trifluoromethylpyridin- 2- yl)piperazin- 1- yl)(5- methanesulfonyl- 2- (2,2,2- trifluoro- 1- methylethoxy)phenyl)methanoneIBA 01/2023 - 08/2022
2	Neurotransmitter Agents (Neurotransmitter)IBA 01/2023 - 01/2013
2	(R)- (N- (3- (4'- fluorophenyl)- 3- (4'- phenylphenoxy)propyl))sarcosineIBA 08/2022 - 11/2021
2	Serotonin 5-HT2 Receptor AntagonistsIBA 08/2022 - 01/2018
2	alpha-SynucleinIBA 01/2022 - 03/2011
2	Therapeutic UsesIBA 11/2021 - 01/2021
2	5-HT3 Serotonin Receptors (5 HT3 Receptor)IBA 01/2021 - 03/2020
2	EnzymesIBA 11/2020 - 01/2007
2	Moclobemide (Arima)IBA 11/2020 - 11/2020
2	Mirtazapine (Rexer)FDA LinkGeneric 05/2020 - 03/2017
2	MianserinIBA 05/2020 - 01/2018
2	Antipsychotic Agents (Antipsychotics)IBA 01/2017 - 05/2012
2	Catechol O-Methyltransferase (Methyltransferase, Catechol)IBA 01/2016 - 03/2013
2	3- ((4- (4- chlorophenyl)piperazin- 1- yl)methyl)- 1H- pyrrolo(2,3- b)pyridineIBA 02/2015 - 08/2012
2	N- methyl- 1- cyclopropyl- 1- piperonylmethylamineIBA 07/2014 - 01/2012
2	N-Methyl-3,4-methylenedioxyamphetamine (MDMA)IBA 05/2012 - 05/2011
2	N- (2- (4- (2- methoxyphenyl)- 1- piperazinyl)ethyl)- N- (2- pyridinyl)cyclohexanecarboxamideIBA 05/2012 - 01/2012
1	Lamotrigine (Lamictal)FDA LinkGeneric 01/2024
1	Gabapentin (Neurontin)FDA LinkGeneric 01/2024
1	Pregabalin (Lyrica)FDA Link 01/2024
1	Anticonvulsants (Antiepileptic Drugs)IBA 01/2024
1	Metronidazole (Metric)FDA LinkGeneric 01/2024
1	LY 2140023IBA 10/2023
1	ProdrugsIBA 10/2023
1	nelotanserinIBA 07/2023
1	safinamideIBA 01/2023
1	N-Methylaspartate (NMDA)IBA 01/2023
1	eglumetadIBA 08/2022
1	N- (4- (2- methoxyphenoxy)phenyl)- N- (2,2,2- trifluoroethylsulfonyl)pyrid- 3- ylmethylamineIBA 08/2022
1	LY 341495IBA 08/2022
1	ButyrylcholinesteraseIBA 01/2022
1	Cholinergic Agents (Cholinergics)IBA 01/2022
1	Rivastigmine (Exelon)FDA LinkGeneric 01/2022
1	Serotonin 5-HT3 Receptor AntagonistsIBA 01/2021
1	Antidepressive Agents (Antidepressants)IBA 05/2020
1	Venlafaxine Hydrochloride (Effexor)FDA LinkGeneric 05/2020
1	Escitalopram FDA Link 05/2020
1	Amoxapine (Asendin)FDA Link 05/2020
1	Citalopram FDA LinkGeneric 05/2020
1	Clomipramine (Anafranil)FDA LinkGeneric 05/2020
1	nefazodone (Serzone)FDA LinkGeneric 12/2018
1	Adrenergic Receptors (Adrenergic Receptor)IBA 01/2018
1	Trazodone (Trittico)FDA LinkGeneric 01/2018
1	pimavanserinIBA 03/2017
1	Aripiprazole (Abilify)FDA Link 01/2017
1	Norepinephrine (Noradrenaline)FDA LinkGeneric 01/2016
1	Dopamine Uptake Inhibitors (Dopamine Reuptake Inhibitors)IBA 01/2016
1	Monoamine Oxidase Inhibitors (Monoamine Oxidase Inhibitor)IBA 01/2016
1	Adenosine (Adenocard)FDA LinkGeneric 12/2015
1	3- chloro- 4- fluorophenyl- (4- fluoro- 4- (((5- methylpyrimidin- 2- ylmethyl)amino)methyl)piperidin- 1- yl)methanoneIBA 10/2015
1	Pioglitazone (Actos)FDA Link 03/2015
1	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 03/2015
1	PPAR gammaIBA 03/2015
1	Dopamine D4 Receptors (Dopamine D4 Receptor)IBA 02/2015
1	Serotonin Plasma Membrane Transport Proteins (Serotonin Transporter)IBA 01/2015

Therapy/Procedure

16	Therapeutics 11/2021 - 01/2010